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Caldesmon 抗体 (AA 500-550)

This anti-Caldesmon antibody is a 兔 多克隆 antibody detecting Caldesmon in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7455008
发货至: 中国

Quick Overview for Caldesmon 抗体 (AA 500-550) (ABIN7455008)

抗原

See all Caldesmon (CALD1) 抗体
Caldesmon (CALD1) (Caldesmon 1 (CALD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Caldesmon antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 500-550

    原理

    Rabbit anti-Caldesmon Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 500 and 550

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Caldesmon (CALD1) (Caldesmon 1 (CALD1))

    别名

    Caldesmon

    背景

    Background: Caldesmon is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of caldesmon possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction [taken from NCBI Entrez Gene (Gene ID: 800)].

    基因ID

    800

    NCBI登录号

    NP_149129

    UniProt

    Q05682

    途径

    Myometrial Relaxation and Contraction
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