XPO5 抗体 (AA 1154-1204)
Quick Overview for XPO5 抗体 (AA 1154-1204) (ABIN7454998)
抗原
See all XPO5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1154-1204
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原理
- Rabbit anti-Exportin-5 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1154 and 1204
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亚型
- IgG
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anti-Exportin 5 (XPO5) (AA 1-280) antibody
XPO5 适用: 人 WB, IF, IP, ELISA 宿主: 小鼠 Monoclonal 2C5-1B3 unconjugated
anti-Exportin 5 (XPO5) (AA 925-1204) antibodyXPO5 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1-1204) antibodyXPO5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1-1204) antibodyXPO5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exportin 5 (XPO5) antibodyXPO5 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 190-239) antibodyXPO5 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 182-231) antibodyXPO5 适用: 人, 小鼠, 大鼠, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1115-1164) antibodyXPO5 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (N-Term) antibodyXPO5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 2-180) antibodyXPO5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- XPO5 (Exportin 5 (XPO5))
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别名
- Exportin-5
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背景
- Background: Exportin-5 mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). Exportin-5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its active GTP-bound form. Proteins containing dsRBDs can associate with this trimeric complex through the RNA. Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause disassembly of the complex and release of the cargo from the export receptor. Exportin-5 then returns to the nuclear compartment by diffusion through the nuclear pore complex, to mediate another round of transport [taken from the Universal Protein Resource (UniProt) Q9HAV4].
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基因ID
- 57510
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NCBI登录号
- NP_065801
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UniProt
- Q9HAV4
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途径
- Regulatory RNA Pathways, Protein targeting to Nucleus
抗原
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