EXOSC10 抗体 (AA 750-800)
Quick Overview for EXOSC10 抗体 (AA 750-800) (ABIN7454997)
抗原
See all EXOSC10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 750-800
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原理
- Rabbit anti-EXOSC10 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 750 and 800
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- EXOSC10 (Exosome Component 10 (EXOSC10))
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别名
- EXOSC10
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背景
- Background: Exosome component 10 (EXOSC10) is a putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRN. It is also involved in the elimination of RNA-processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs [taken from the Universal Protein Resource (UniProt) Q01780].
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基因ID
- 5394
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NCBI登录号
- NP_001001998
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UniProt
- Q01780
抗原
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