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EXOSC10 抗体 (AA 200-250)

This anti-EXOSC10 antibody is a 兔 多克隆 antibody detecting EXOSC10 in WB, IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7454996
发货至: 中国

Quick Overview for EXOSC10 抗体 (AA 200-250) (ABIN7454996)

抗原

See all EXOSC10 抗体
EXOSC10 (Exosome Component 10 (EXOSC10))

适用

  • 36
  • 22
  • 6
  • 6
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 35
  • 2

克隆类型

  • 35
  • 2
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EXOSC10 antibody is un-conjugated

应用范围

  • 31
  • 13
  • 13
  • 13
  • 8
  • 6
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-250

    原理

    Rabbit anti-EXOSC10 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 200 and 250

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    EXOSC10 (Exosome Component 10 (EXOSC10))

    别名

    EXOSC10

    背景

    Background: Exosome component 10 (EXOSC10) is a putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRN. It is also involved in the elimination of RNA-processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs [taken from the Universal Protein Resource (UniProt) Q01780].

    基因ID

    5394

    NCBI登录号

    NP_001001998

    UniProt

    Q01780
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