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BAG3 抗体 (AA 525-575)

This anti-BAG3 antibody is a 兔 多克隆 antibody detecting BAG3 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454868
发货至: 中国

Quick Overview for BAG3 抗体 (AA 525-575) (ABIN7454868)

抗原

See all BAG3 抗体
BAG3 (BCL2-Associated Athanogene 3 (BAG3))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAG3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
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    AA 525-575

    原理

    Rabbit anti-BAG3 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 525 and 575

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    BAG3 (BCL2-Associated Athanogene 3 (BAG3))

    别名

    BAG3

    背景

    Background: BAG3 (BCL2-associated athanogene 3) BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. BAG3 contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All three proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner [taken from NCBI Entrez Gene (Gene ID: 9531)].

    基因ID

    9531

    NCBI登录号

    NP_004272

    UniProt

    O95817
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