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FLCN 抗体 (AA 1-50)

This anti-FLCN antibody is a 兔 多克隆 antibody detecting FLCN in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454827
发货至: 中国

Quick Overview for FLCN 抗体 (AA 1-50) (ABIN7454827)

抗原

See all FLCN 抗体
FLCN (Folliculin (FLCN))

适用

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宿主

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克隆类型

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多克隆

标记

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This FLCN antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
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    AA 1-50

    原理

    Rabbit anti-BHD Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    FLCN (Folliculin (FLCN))

    别名

    BHD

    物质类

    Amino Acid

    背景

    Background: Defects in the folliculin (FLCN) gene are the cause of Birt-Hogg-Dube syndrome (BHD) [MIM:135150]. BHD is a rare autosomal dominant genodermatosis characterized by hair follicle hamartomas (fibrofolliculomas), kidney tumors, and spontaneous pneumothorax. Fibrofolliculomas are part of the triad of BHD skin lesions that also includes trichodiscomas and acrochordons. Defects in FLCN may also be the cause of primary spontaneous pneumothorax (PSP) [MIM:173600], a condition in which air is present in the pleural space in the absence of a precipitating event, such as trauma or lung disease. Folliculin may be a tumor suppressor involved in colorectal and renal cell tumorigenesis [taken from the Universal Protein Resource (UniProt) Q8NFG4].

    基因ID

    201163

    NCBI登录号

    NP_659434

    UniProt

    Q8NFG4

    途径

    Cell-Cell Junction Organization
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