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KDM5B 抗体 (AA 1494-1544)

This anti-KDM5B antibody is a 兔 多克隆 antibody detecting KDM5B in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454788
发货至: 中国

Quick Overview for KDM5B 抗体 (AA 1494-1544) (ABIN7454788)

抗原

See all KDM5B 抗体
KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

适用

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宿主

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克隆类型

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多克隆

标记

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This KDM5B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 1494-1544

    原理

    Rabbit anti-JARID1B Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1494 and 1544

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

    别名

    JARID1B

    背景

    Background: JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer.

    基因ID

    10765

    NCBI登录号

    NP_006609

    UniProt

    Q9UGL1

    途径

    Warburg Effect
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