PUS1 抗体 (AA 377-427)
Quick Overview for PUS1 抗体 (AA 377-427) (ABIN7454768)
抗原
See all PUS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 377-427
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原理
- Rabbit anti-PUS1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 377 and 427
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亚型
- IgG
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anti-Pseudouridylate Synthase 1 (PUS1) (AA 1-399) antibody
PUS1 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) antibodyPUS1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 1-399) antibodyPUS1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 1-427) antibodyPUS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 88-137) antibodyPUS1 适用: 人, 小鼠, 大鼠, 兔, 绵羊, 马, 豚鼠, 犬, Cow, Hamster, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 21-70) antibodyPUS1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (C-Term) antibodyPUS1 适用: 小鼠, 大鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 308-427) antibodyPUS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (N-Term) antibodyPUS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 322-350), (C-Term) antibodyPUS1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32559 unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PUS1 (Pseudouridylate Synthase 1 (PUS1))
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别名
- PUS1
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背景
- Background: Pus1 (pseudouridylate synthase 1) is an enzyme that converts uridine to pseudouridine in non-coding RNA substrates. Pus1 modifies uridines at specific positions in a subset of tRNAs. Pseudouridylation is known to affect the structure of tRNAs and stabilize base-stacking and base-pairing in the anticodon loop. Pus1 activity is important for proper folding and function of tRNAs. Pus1 has also been shown to pseudouridylate SRA (steroid receptor RNA activator) and function as a coactivator. Defects in pseudouridylation are associated with the human disease, MLASA (myopathy with lactic acidosis and sideroblastic anemia), an autosomal recessive oxidative phosphorylataion disorder specific to skeletal muscle and bone marrow.
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基因ID
- 80324
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NCBI登录号
- NP_079491
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UniProt
- Q9Y606
抗原
-
