WDR77 抗体 (AA 292-342)
Quick Overview for WDR77 抗体 (AA 292-342) (ABIN7454760)
抗原
See all WDR77 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 292-342
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原理
- Rabbit anti-WDR77/MEP50 Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 292 and 342
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- WDR77 (WD Repeat Domain 77 (WDR77))
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别名
- WDR77/MEP50
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背景
- Background: WDR77/MEP50 is a component of the methylosome, a large protein arginine methyltransferase complex that modifies specific arginines to dimethylarginines in splicesomal Sm proteins. WDR77/MEP50 associates with the methyltransferase JBP1 (PRMT5) and is important for methylosome activity. WDR77/MEP50 has also been shown to associate with the polycomb group protein, SUZ12, and histone H2A. In this context, WDR77/MEP50 is proposed to function as an adaptor between PRMT5 and its substrate H2A to regulate transcription.
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基因ID
- 79084
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NCBI登录号
- NP_077007
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UniProt
- Q9BQA1
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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