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AKAP8L 抗体 (AA 596-646)

AKAP8L 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7454742
发货至: 中国
  • 抗原 See all AKAP8L 抗体
    AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
    抗原表位
    • 11
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 596-646
    适用
    • 38
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 38
    克隆类型
    • 38
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKAP8L antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 8
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    原理
    Rabbit anti-AKAP8L/HA95 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 596 and 646
    亚型
    IgG
    Top Product
    Discover our top product AKAP8L Primary Antibody
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
    别名
    AKAP8L/HA95 (AKAP8L 产品)
    别名
    HA95 antibody, HAP95 antibody, NAKAP antibody, NAKAP95 antibody, Nakap95 antibody, zgc:85966 antibody, AKAP8L antibody, A-kinase anchoring protein 8 like antibody, A kinase (PRKA) anchor protein 8-like antibody, A-kinase anchoring protein 8 like L homeolog antibody, AKAP8L antibody, Akap8l antibody, akap8l antibody, akap8l.L antibody
    背景
    Background: AKAP8L/HA95 is a PKA anchoring protein that is localized to the nuclear envelope and associates with chromatin upon nuclear envelope breakdown during mitosis. AKAP8L/HA95 has been found to play an important role in the initiation of DNA replication and may function as a scaffold for proteins such as MCM2 and LAP2beta. Additionally, AKAP8L/HA95 has been shown to co-locate with the PKA C subunit in splicing factor compartments and is involved in the regulation of pre-mRNA splicing. Further support for a scaffolding and splicing role in the nucleus comes from the observation that AKAP8L/HA95 colocalizes with HypA, a splicing-like factor, and through this association may function as a docking site for the nuclear accumulation of Huntington protein as seen in Huntington's disease.
    基因ID
    26993
    NCBI登录号
    NP_055186
    UniProt
    Q9ULX6
    途径
    SARS-CoV-2 Protein Interactome
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