AKAP8L 抗体 (AA 596-646)
Quick Overview for AKAP8L 抗体 (AA 596-646) (ABIN7454742)
抗原
See all AKAP8L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 596-646
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原理
- Rabbit anti-AKAP8L/HA95 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 596 and 646
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亚型
- IgG
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anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (C-Term) antibody
AKAP8L 适用: 人, 犬, 大鼠, 马, Cow, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (AA 1-240) antibodyAKAP8L 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (C-Term) antibodyAKAP8L 适用: 人, 小鼠, 犬, 大鼠, 马, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (AA 351-400) antibodyAKAP8L 适用: 人, 犬, 大鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (AA 485-512), (C-Term) antibodyAKAP8L 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB36906 unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
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别名
- AKAP8L/HA95
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背景
- Background: AKAP8L/HA95 is a PKA anchoring protein that is localized to the nuclear envelope and associates with chromatin upon nuclear envelope breakdown during mitosis. AKAP8L/HA95 has been found to play an important role in the initiation of DNA replication and may function as a scaffold for proteins such as MCM2 and LAP2beta. Additionally, AKAP8L/HA95 has been shown to co-locate with the PKA C subunit in splicing factor compartments and is involved in the regulation of pre-mRNA splicing. Further support for a scaffolding and splicing role in the nucleus comes from the observation that AKAP8L/HA95 colocalizes with HypA, a splicing-like factor, and through this association may function as a docking site for the nuclear accumulation of Huntington protein as seen in Huntington's disease.
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基因ID
- 26993
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NCBI登录号
- NP_055186
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UniProt
- Q9ULX6
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途径
- SARS-CoV-2 Protein Interactome
抗原
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