Filamin A 抗体 (AA 1725-1775)
Quick Overview for Filamin A 抗体 (AA 1725-1775) (ABIN7454720)
抗原
See all Filamin A (FLNA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1725-1775
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原理
- Rabbit anti-Filamin A Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1725 and 1775
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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别名
- Filamin A
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背景
- Background: Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.
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基因ID
- 2316
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NCBI登录号
- NP_001447
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UniProt
- P21333
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途径
- TCR Signaling, Maintenance of Protein Location
抗原
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