TOP2B 抗体 (C-Term)
Quick Overview for TOP2B 抗体 (C-Term) (ABIN7454697)
抗原
See all TOP2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-Topo II Beta Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1570 and C-term
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亚型
- IgG
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应用备注
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IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))
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别名
- Topo II Beta
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背景
- Background: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II beta is one of two described isoforms that are likely products of a gene duplication event. TopoII beta is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.
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基因ID
- 7155
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NCBI登录号
- NP_001059
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UniProt
- Q02880
抗原
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