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TOP2B 抗体 (C-Term)

This anti-TOP2B antibody is a 兔 多克隆 antibody detecting TOP2B in WB, IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7454697
发货至: 中国

Quick Overview for TOP2B 抗体 (C-Term) (ABIN7454697)

抗原

See all TOP2B 抗体
TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This TOP2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    C-Term

    原理

    Rabbit anti-Topo II Beta Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1570 and C-term

    亚型

    IgG
  • 应用备注

    IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))

    别名

    Topo II Beta

    背景

    Background: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II beta is one of two described isoforms that are likely products of a gene duplication event. TopoII beta is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.

    基因ID

    7155

    NCBI登录号

    NP_001059

    UniProt

    Q02880
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