DEC1 抗体 (C-Term)
Quick Overview for DEC1 抗体 (C-Term) (ABIN7454653)
抗原
See all DEC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-DEC1 Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 350 and C-term
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亚型
- IgG
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应用备注
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IHC: 1:500 to 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- DEC1 (Deleted in Esophageal Cancer 1 (DEC1))
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别名
- DEC1
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背景
- Background: DEC1 is a basic helix-loop-helix transcription factor that appears to play a role in cell differentiation, proliferation, apoptosis, and the circadian rhythm. DEC1 is able to promote chondrogenic and osteogenic differentiation in mesenchymal stem cells by activating transcription of bone-related genes. When it is overexpressed in cells it can suppress apoptosis by blocking caspase activation and inducing transcription of survivin. DEC1 has also been found to play a role mammalian in circadian rhythm as a suppressor of the CLOCK/BMAL1 promoter.
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基因ID
- 8553
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NCBI登录号
- NP_003661
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UniProt
- O14503
抗原
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