CARM1 抗体 (C-Term)
Quick Overview for CARM1 抗体 (C-Term) (ABIN7454627)
抗原
See all CARM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-CARM1 Antibody, Affinity Purified
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预测反应
- Rat
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纯化方法
- Affinity Purified
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免疫原
- Between AA 550 and C-term
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亚型
- IgG
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应用备注
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IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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别名
- CARM1
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背景
- Background: Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4, has been shown to interact with and methylate RNA splicing factors such as CA150 that link transcription to splicing. In this context, CARM1 may be involved in spinal muscular atrophy pathogenesis. CARM1 has also been found to be a coactivator of the NFKappaB transcription factor and the androgen receptor.
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基因ID
- 10498
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NCBI登录号
- NP_954592
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UniProt
- Q86X55
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
抗原
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