NCOA1 抗体 (AA 600-650)
Quick Overview for NCOA1 抗体 (AA 600-650) (ABIN7454614)
抗原
See all NCOA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-650
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原理
- Rabbit anti-SRC1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 600 and 650
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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别名
- SRC1
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背景
- Background: Steroid receptor coactivator 1 (SRC1) belongs to the SRC family of proteins that interacts with nuclear receptors to facilitate transcription. The 3 homologous members of this family are SRC-1 (NCoA-1), SRC-2 (GRIP1, TIF2, or NcoA-2), and SRC-3 (p/CIP, RAC3, ACTR, AIB1, or TRAM-1). SRC1contains histone acetyltransferase (HAT) activities and may facilitate transcription through chromatin remodeling. SRCs associate with p300/CBP-associated factor and CREB binding protein (CBP) as part of a multisubunit coactivating complex.
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基因ID
- 8648
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NCBI登录号
- NP_003734
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UniProt
- Q15788
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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