NMNAT1 抗体 (AA 229-279)
Quick Overview for NMNAT1 抗体 (AA 229-279) (ABIN7454578)
抗原
See all NMNAT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 229-279
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原理
- Rabbit anti-NMNAT1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 229 and 279
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))
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别名
- NMNAT1
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背景
- Background: Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. NMNAT1 is an enzyme which catalyzes a key step in the biosynthesis of the coenzyme NAD. NMNAT1 is one of several nicotinamide nucleotide adenylyltransferases. Studies in Drosophila and mammalian neurons have shown NMNAT1 can confer protection to damaged neurons. This protection requires enzymatic activity which increases NAD levels and activates a nuclear deacetylase which is the protective molecul [taken from NCBI Entrez Gene (Gene ID: 64802)].
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基因ID
- 64802
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NCBI登录号
- NP_073624
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UniProt
- Q9HAN9
抗原
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