DNMT3A 抗体 (AA 125-175)
Quick Overview for DNMT3A 抗体 (AA 125-175) (ABIN7454575)
抗原
See all DNMT3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 125-175
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原理
 - Rabbit anti-DNMT3A Antibody, Affinity Purified
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纯化方法
 - Affinity Purified
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免疫原
 - Between AA 125 and 175
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亚型
 - IgG
 
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
 - 仅限研究用
 
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浓度
 - 1000 μg/mL
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缓冲液
 - Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C
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有效期
 - 12 months
 
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- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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别名
 - DNMT3A
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背景
 - Background: DNA cytosine methyltransferase 3A2 (DNMT3A) is required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. DNMT3A modifies DNA in a non-processive manner and also methylates non-CpG sites. It may preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. DNMT3A plays a role in paternal and maternal imprinting and is required for methylation of most imprinted loci in germ cells [taken from the Universal Protein Resource (UniProt) Q9Y6K1].
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基因ID
 - 1788
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NCBI登录号
 - NP_783328
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UniProt
 - Q9Y6K1
 
抗原
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