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PUF60 抗体 (AA 509-559)

This 兔 多克隆 anti-PUF60 antibody specifically detects PUF60 in WB 和 IHC (fp). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7454555
发货至: 中国
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Quick Overview for PUF60 抗体 (AA 509-559) (ABIN7454555)

抗原

See all PUF60 抗体
PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

适用

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  • 2
人, 小鼠

宿主

  • 64
  • 6
  • 1

克隆类型

  • 65
  • 6
多克隆

标记

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This PUF60 antibody is un-conjugated

应用范围

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  • 3
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Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
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    • 1
    • 1
    • 1
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    AA 509-559

    原理

    Rabbit anti-PUF60 Antibody, Affinity Purified

    预测反应

    Rat,Bovine,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 509 and 559

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: Not recommended

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

    别名

    PUF60

    背景

    Background: Poly-U binding splicing factor 60KDa (PUF60) is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. PUF60 is implicated in the xeroderma pigmentosum disorder [taken from NCBI Entrez Gene (Gene ID: 22827)].

    基因ID

    22827

    NCBI登录号

    NP_510965

    UniProt

    Q9UHX1
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