Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 450-500) 抗体
Quick Overview for Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 450-500) 抗体 (ABIN7454475)
抗原
See all Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-500
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原理
- Rabbit anti-Cbl-b Antibody, Affinity Purified
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预测反应
- Mouse,Rat
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纯化方法
- Affinity Purified
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免疫原
- between AA 450 and 500
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB)
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别名
- Cbl-b
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背景
- Background: Cbl-b is an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Cbl-b negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways [taken from the Universal Protein Resource (UniProt) Q13191].
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基因ID
- 868
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NCBI登录号
- NP_733762
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UniProt
- Q13191
抗原
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