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UBR4 抗体 (AA 150-200)

UBR4 适用: 人 IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7454442
发货至: 中国
  • 抗原 See all UBR4 抗体
    UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-200
    适用
    • 23
    • 13
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 18
    • 4
    • 1
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBR4 antibody is un-conjugated
    应用范围
    • 12
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    原理
    Rabbit anti-p600 Antibody, Affinity Purified
    预测反应
    Mouse,Rat
    纯化方法
    Affinity Purified
    免疫原
    between AA 150 and 200
    亚型
    IgG
    Top Product
    Discover our top product UBR4 Primary Antibody
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 10 μg/mg lysate

    WB: Not recommended. Use rabbit anti-p600 antibody A302-278A or A302-279A.

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
    别名
    p600 (UBR4 产品)
    别名
    ZUBR1 antibody, RBAF600 antibody, p600 antibody, 1810009A16Rik antibody, A930005E13Rik antibody, D930005K06Rik antibody, Gm1032 antibody, Gm1666 antibody, N28143 antibody, Zubr1 antibody, mKIAA0462 antibody, Rbaf600 antibody, ubiquitin protein ligase E3 component n-recognin 4 antibody, E3 ubiquitin-protein ligase UBR4 antibody, UBR4 antibody, Ubr4 antibody, LOC100511934 antibody
    背景
    Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].
    基因ID
    23352
    NCBI登录号
    NP_065816
    UniProt
    Q5T4S7
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