PAGR1 抗体 (AA 204-254)
Quick Overview for PAGR1 抗体 (AA 204-254) (ABIN7454425)
抗原
See all PAGR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 204-254
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原理
- Rabbit anti-PA1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 204 and 254
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亚型
- IgG
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anti-PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1) (C-Term) antibody
PAGR1 适用: 人, 小鼠 WB, IHC, IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
anti-PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1) (AA 38-87) antibodyPAGR1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1) (N-Term) antibodyPAGR1 适用: 人, 马, Cow, 山羊, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-PA1 antibody A301-978A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))
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别名
- PA1
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背景
- Background: PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.
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基因ID
- 79447
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NCBI登录号
- NP_078792
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UniProt
- Q9BTK6
抗原
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