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CHD3 抗体 (AA 1950-2000)

This anti-CHD3 antibody is a 兔 多克隆 antibody detecting CHD3 in IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7454393
发货至: 中国

Quick Overview for CHD3 抗体 (AA 1950-2000) (ABIN7454393)

抗原

See all CHD3 抗体
CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CHD3 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
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    AA 1950-2000

    原理

    Rabbit anti-CHD3 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1950 and 2000

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-CHD3 antibody A301-219A.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

    别名

    CHD3

    背景

    Background: CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.

    基因ID

    1107

    NCBI登录号

    NP_001005273

    UniProt

    Q12873
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