CHD3 抗体 (AA 1950-2000)
Quick Overview for CHD3 抗体 (AA 1950-2000) (ABIN7454393)
抗原
See all CHD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1950-2000
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原理
- Rabbit anti-CHD3 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1950 and 2000
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-CHD3 antibody A301-219A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
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别名
- CHD3
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背景
- Background: CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.
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基因ID
- 1107
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NCBI登录号
- NP_001005273
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UniProt
- Q12873
抗原
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