PELP1 抗体 (AA 25-75)
Quick Overview for PELP1 抗体 (AA 25-75) (ABIN7454378)
抗原
See all PELP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-75
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原理
- Rabbit anti-PELP1/MNAR Antibody, Affinity Purified
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预测反应
- Monkey
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纯化方法
- Affinity Purified
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免疫原
- between AA 25 and 75
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-PELP1/MNAR antibody A300-180A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))
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别名
- PELP1/MNAR
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背景
- Background: PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the ""signalsome"" involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.
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基因ID
- 27043
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UniProt
- Q8IZL8
抗原
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