REST 抗体 (AA 800-850)
Quick Overview for REST 抗体 (AA 800-850) (ABIN7454366)
抗原
See all REST 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 800-850
-
原理
- Rabbit anti-REST Antibody, Affinity Purified
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 800 and 850
-
亚型
- IgG
-
-
-
-
应用备注
-
IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-REST antibody A300-540A.
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- REST (RE1-Silencing Transcription Factor (REST))
-
别名
- REST
-
背景
- Background: RE1-Silencing Transcription Factor (REST) is a transcriptional repressor that silences neuronal gene expression in non-neuronal cells by binding to the neuron-restrictive silencer element (NRSE). REST is a Kruppel-type zinc finger transcription factor that mediates repression through its interaction with the mSin3 and CoREST corepressors and the HDAC1 and HDAC2 histone deacetylases.
-
基因ID
- 5978
-
NCBI登录号
- NP_005603
-
UniProt
- Q13127
-
途径
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
-