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Recombinant ThPok (AA 250-300) 抗体

The 兔 单克隆 anti-ThPok antibody (Clone BLR191J) (ABIN7453988) specifically detects ThPok in IP, WB, FACS, ICC 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7453988
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant ThPok (AA 250-300) 抗体 (ABIN7453988)

抗原

ThPok

抗体类型

Recombinant Antibody

适用

人, 小鼠

宿主

  • 2

克隆类型

  • 1
  • 1
单克隆

标记

  • 2
非结合性

应用范围

Immunoprecipitation (IP), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

克隆位点

BLR191J
  • 抗原表位

    • 1
    • 1
    AA 250-300

    原理

    Rabbit anti-ThPOK Recombinant Monoclonal Antibody [BLR191J] - BSA-Free

    纯化方法

    Purified

    免疫原

    between AA 250 and 300

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1000 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    ThPok

    背景

    ZBTB7B is a transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. ZBTB7B is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is also a transcriptional repressor of the collagen COL1A1 and COL1A2 genes and may also function as a repressor of fibronectin and possibly other extracellular matrix genes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O15156].

    基因ID

    51043

    UniProt

    O15156
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