Recombinant ThPok (AA 250-300) 抗体
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Quick Overview for Recombinant ThPok (AA 250-300) 抗体 (ABIN7453988)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 250-300
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原理
- Rabbit anti-ThPOK Recombinant Monoclonal Antibody [BLR191J] - BSA-Free
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纯化方法
- Purified
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免疫原
- between AA 250 and 300
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1000 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- ThPok
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背景
- ZBTB7B is a transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. ZBTB7B is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is also a transcriptional repressor of the collagen COL1A1 and COL1A2 genes and may also function as a repressor of fibronectin and possibly other extracellular matrix genes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O15156].
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基因ID
- 51043
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UniProt
- O15156
抗原
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