Polybromo 1 抗体 (AA 1639-1689)
Quick Overview for Polybromo 1 抗体 (AA 1639-1689) (ABIN7453903)
抗原
See all Polybromo 1 (PBRM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1639-1689
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原理
- Rabbit anti-PBRM1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1639 and 1689
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亚型
- IgG
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anti-Polybromo 1 (PBRM1) (AA 1-306) antibody
PBRM1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polybromo 1 (PBRM1) antibodyPBRM1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Polybromo 1 (PBRM1) (AA 1-306) antibodyPBRM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polybromo 1 (PBRM1) (AA 1511-1560) antibodyPBRM1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 兔, Bat, 小鸡, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polybromo 1 (PBRM1) (N-Term) antibodyPBRM1 适用: 人, 小鼠 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Polybromo 1 (PBRM1) (N-Term) antibodyPBRM1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polybromo 1 (PBRM1) antibodyPBRM1 适用: 人 WB 宿主: 小鼠 Monoclonal 6C2 unconjugated
anti-Polybromo 1 (PBRM1) (AA 1121-1155), (C-Term) antibodyPBRM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51306 unconjugated
anti-Polybromo 1 (PBRM1) (AA 31-80) antibodyPBRM1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polybromo 1 (PBRM1) (AA 1-306) antibodyPBRM1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IHC: 1:1000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Polybromo 1 (PBRM1)
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别名
- PBRM1
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背景
- Background: The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PBRM1 is a component of the SWI/SNF-B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PBRM1 has been proposed to function as a tumor suppressor protein. Recently, PBRM1 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21.
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基因ID
- 55193
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UniProt
- Q86U86
抗原
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