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Recombinant Liver Arginase 抗体 (AA 1-322)

This anti-Liver Arginase antibody is a 兔 单克隆 antibody detecting Liver Arginase in WB, IHC (fp) 和 IP. Suitable for 小鼠.
产品编号 ABIN7453894
发货至: 中国

Quick Overview for Recombinant Liver Arginase 抗体 (AA 1-322) (ABIN7453894)

抗原

See all Liver Arginase (ARG1) 抗体
Liver Arginase (ARG1) (Arginase, Liver (ARG1))

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

  • 114
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克隆类型

  • 109
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  • 1
单克隆

标记

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This Liver Arginase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

克隆位点

BLR161J
  • 抗原表位

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    AA 1-322

    原理

    Rabbit anti-Arginase 1 Recombinant Monoclonal Antibody [BLR161J]

    免疫原

    residues 1-322 (FL)

    亚型

    IgG
  • 应用备注

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 20 μL/1 mg lysate

    WB: 01:01,00

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Liver Arginase (ARG1) (Arginase, Liver (ARG1))

    别名

    Arginase 1

    背景

    Background: Arginase1 is a key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively, the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.  [taken from the Universal Protein Resource (UniProt) P05089].

    基因ID

    11846

    NCBI登录号

    NP_031508

    UniProt

    Q61176

    途径

    Cellular Response to Molecule of Bacterial Origin
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