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DHX9 抗体 (C-Term)

This anti-DHX9 antibody is a 兔 多克隆 antibody detecting DHX9 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453848
发货至: 中国

Quick Overview for DHX9 抗体 (C-Term) (ABIN7453848)

抗原

See all DHX9 抗体
DHX9 (ATP-Dependent RNA Helicase A (DHX9))

适用

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宿主

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克隆类型

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多克隆

标记

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This DHX9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    C-Term

    原理

    Rabbit anti-DHX9 Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 1220 and C-term

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    DHX9 (ATP-Dependent RNA Helicase A (DHX9))

    别名

    DHX9

    背景

    Background: DHX9 is a member of the DEAH box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAH box proteins also exhibit functions involved in transcriptional regulation. DHX9 has been shown to act as a bridge between CREB-binding protein (CBP) and RNA polymerase II to coactivate CBP-dependent transcription. A similar observation has been reported for an interaction with BRCA1. DHX9 also exhibits activities associated with nuclear export of retroviral RNAs, translation, RNA editing, and snRNP assembly.

    基因ID

    1660

    UniProt

    Q08211
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