KPNA4 抗体 (AA 471-521)
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Quick Overview for KPNA4 抗体 (AA 471-521) (ABIN7453718)
抗原
See all KPNA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 471-521
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原理
- Rabbit anti-KPNA4 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 471 and 521
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亚型
- IgG
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anti-Karyopherin (Importin) alpha 4 (KPNA4) (AA 1-240) antibody
KPNA4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) (C-Term) antibodyVerified KPNA4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) (AA 51-239) antibodyKPNA4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) (N-Term) antibodyKPNA4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) antibodyKPNA4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) (C-Term) antibodyKPNA4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) (full length) antibodyKPNA4 适用: 小鼠 WB, ELISA 宿主: 大鼠 Monoclonal 3D10 unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) (AA 1-100) antibodyKPNA4 适用: 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) (AA 471-521) antibodyKPNA4 适用: 人, 小鼠, Cow, 犬, 马, 兔, 豚鼠 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) alpha 4 (KPNA4) (AA 38-87) antibodyKPNA4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
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别名
- KPNA4
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背景
- Background: KPNA4 (karyopherin alpha 4), also known as importin alpha 3, is a member of the importin alpha family of proteins which includes KPNA1 (importin alpha 5), KPNA2 (importin alpha 1), KPNA3 (importin alpha 4), KPNA4 (importin alpha 3), KPNA5 (importin alpha 6), and KPNA6 (importin alpha 7). The importin alpha family of proteins plays a role in the import of proteins from the cytoplasm to the nucleus. The import of proteins from the cytoplasm to the nucleus involves docking the protein to receptors associated with the nuclear pore complex (NPC) followed by translocation through the nuclear pore. Importin alpha proteins bind the nuclear localization signal (NLS) of cargo proteins and function as adaptor proteins for the nuclear pore receptor KPNB1 (importin beta 1). KPNB1 is responsible for docking the importin-cargo complex to the cytoplasmic side of the NPC for its translocation through the NPC. KPNA3 (Importin alpha 4) and KPNA4 (importin alpha 3) have been reported to mediate the nuclear import of TNF-alpha induced nuclear import of NF-kappaB p50/p65 heterodimers. RNA interference experiments have shown that KPNA4 is important for HeLa cell proliferation and the nuclear import of the Ran guanine nucleotide exchange factor, RCC1.
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基因ID
- 3840
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NCBI登录号
- NP_002259
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UniProt
- O00629
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途径
- Protein targeting to Nucleus
抗原
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