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FLII 抗体 (AA 425-475)

This anti-FLII antibody is a 兔 多克隆 antibody detecting FLII in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453708
发货至: 中国

Quick Overview for FLII 抗体 (AA 425-475) (ABIN7453708)

抗原

See all FLII 抗体
FLII (Flightless I Homolog (FLII))

适用

  • 19
  • 13
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 25
  • 1

克隆类型

  • 25
  • 1
多克隆

标记

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  • 4
  • 3
  • 3
This FLII antibody is un-conjugated

应用范围

  • 14
  • 13
  • 10
  • 5
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 425-475

    原理

    Rabbit anti-Flightless-1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 425 and 475

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    FLII (Flightless I Homolog (FLII))

    别名

    Flightless-1

    背景

    Background: Flightless-1 is the human homolog of the drosophila flightless (fli1), a gene required for proper development of flight muscles and essential to embryonic development. It is a member of the gelsolin family of actin-binding proteins, and is highly conserved among vertebrates and invertebrates. The actin-remodeling activity of flightless-1 may have multiple roles in the cell. Studies in transgenic mice indicate a role in wound healing that may involve the regulation of cell migration and proliferation. Flightless-1 has also been found to be associated with complexes involved in transcriptional regulation. It associates with CARM1, a protein arginine methyltransferase, and may function as a nuclear receptor coactivator via this interaction. It has also been shown to associate with the BAF53a subunit of the SWI/SNF-like chromatin remodeling complexes.

    基因ID

    2314

    NCBI登录号

    NP_002009

    UniProt

    Q13045
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