Fatty Acid Synthase 抗体 (AA 2462-2511)
Quick Overview for Fatty Acid Synthase 抗体 (AA 2462-2511) (ABIN7453707)
抗原
See all Fatty Acid Synthase (FASN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2462-2511
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原理
- Rabbit anti-FASN Antibody, Affinity Purified
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预测反应
- Rat,Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 2462 and 2511
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Fatty Acid Synthase (FASN)
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别名
- FASN
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背景
- Background: Fatty acid synthase (FASN) is a multifunctional protein that is mainly involved in catalyzing the synthesis of long-chain fatty acids. FASN has recently been viewed as an important protein involved in carcinogenesis as it has been found to be constitutively active in subsets of carcinomas and is associated with a poor prognosis. The inhibition of FASN activity in cancer cells promotes apoptosis and thus may play a role in maintaining cancer cell survival.
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基因ID
- 2194
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NCBI登录号
- NP_004095
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UniProt
- P49327
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途径
- AMPK Signaling
抗原
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