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EYA3 抗体 (AA 1-30)

This anti-EYA3 antibody is a 兔 多克隆 antibody detecting EYA3 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453703
发货至: 中国

Quick Overview for EYA3 抗体 (AA 1-30) (ABIN7453703)

抗原

See all EYA3 抗体
EYA3 (Eyes Absent Homolog 3 (EYA3))

适用

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宿主

  • 31

克隆类型

  • 31
多克隆

标记

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This EYA3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
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    • 1
    AA 1-30

    原理

    Rabbit anti-EYA3 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1 and 30

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    EYA3 (Eyes Absent Homolog 3 (EYA3))

    别名

    EYA3

    背景

    Background: EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) Q99504].

    基因ID

    2140

    NCBI登录号

    NP_001981

    UniProt

    Q99504

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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