EYA3 抗体 (AA 1-30)
Quick Overview for EYA3 抗体 (AA 1-30) (ABIN7453703)
抗原
See all EYA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 1-30
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原理
 - Rabbit anti-EYA3 Antibody, Affinity Purified
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纯化方法
 - Affinity Purified
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免疫原
 - between AA 1 and 30
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亚型
 - IgG
 
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
 - 仅限研究用
 
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浓度
 - 200 μg/mL
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缓冲液
 - Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C
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有效期
 - 12 months
 
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- EYA3 (Eyes Absent Homolog 3 (EYA3))
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别名
 - EYA3
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背景
 - Background: EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) Q99504].
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基因ID
 - 2140
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NCBI登录号
 - NP_001981
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UniProt
 - Q99504
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途径
 - Positive Regulation of Response to DNA Damage Stimulus
 
抗原
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