DERL1 抗体 (AA 201-251)
Quick Overview for DERL1 抗体 (AA 201-251) (ABIN7453690)
抗原
See all DERL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-251
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原理
- Rabbit anti-Derlin-1 Antibody, Affinity Purified
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预测反应
- Bovine,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 201 and 251
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
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别名
- Derlin-1
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背景
- Background: Derlin-1 (Degradation in endoplasmic reticulum protein 1) is a functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Derlin-1 may act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome [taken from the Universal Protein Resource (UniProt) Q9BUN8].
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基因ID
- 79139
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NCBI登录号
- NP_077271
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UniProt
- Q9BUN8
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途径
- ER-Nucleus Signaling
抗原
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