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INTS6 抗体 (AA 750-800)

This anti-INTS6 antibody is a 兔 多克隆 antibody detecting INTS6 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453687
发货至: 中国

Quick Overview for INTS6 抗体 (AA 750-800) (ABIN7453687)

抗原

See all INTS6 抗体
INTS6 (Integrator Complex Subunit 6 (INTS6))

适用

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宿主

  • 23
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克隆类型

  • 23
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多克隆

标记

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This INTS6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 750-800

    原理

    Rabbit anti-DDX26/DICE1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 750 and 800

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    INTS6 (Integrator Complex Subunit 6 (INTS6))

    别名

    DDX26/DICE1

    背景

    Background: DDX26/DICE1 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX26/DICE1 is a subunit of the integrator complex involved in 3'-end processing of snRNAs. DDX26/DICE1 is implicated as a tumor suppressor, and its ectopic expression has been shown to inhibit tumor cell growth. Alternative names for DDX26/DICE1 include integrator complex subunit 6, Int6, protein deleted in cancer 1, protein DDX26, DBI-1, deleted in cancer 1, INTS6, DDX26A, HDB, Nochl2, and DKFZP434B105.

    基因ID

    26512

    NCBI登录号

    NP_036273

    UniProt

    Q9UL03
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