CASC3 抗体 (AA 653-703)
Quick Overview for CASC3 抗体 (AA 653-703) (ABIN7453674)
抗原
See all CASC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 653-703
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原理
- Rabbit anti-CASC3 Antibody, Affinity Purified
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预测反应
- Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 653 and 703
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
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别名
- CASC3
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背景
- Background: Cancer susceptibility candidate gene 3 protein (CASC3) is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. CASC3 is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles [taken from NCBI Entrez Gene (GeneID: 22794)].
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基因ID
- 22794
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NCBI登录号
- NP_031385
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UniProt
- O15234
抗原
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