Apoptosis Inhibitor 5 抗体 (AA 1-50)
Quick Overview for Apoptosis Inhibitor 5 抗体 (AA 1-50) (ABIN7453657)
抗原
See all Apoptosis Inhibitor 5 (API5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-API5 Antibody, Affinity Purified
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预测反应
- X. laevis,Chicken,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 1 and 50
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Apoptosis Inhibitor 5 (API5)
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别名
- API5
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背景
- Background: API5 (apoptosis inhibitor 5) is an antiapoptotic factor that may have a role in protein assembly. API5 negatively regulates ACIN1. By binding to ACIN1, API5 suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. API5 is also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
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基因ID
- 8539
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NCBI登录号
- XP_508375
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UniProt
- Q9BZZ5
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途径
- Growth Factor Binding
抗原
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