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Apoptosis Inhibitor 5 抗体 (AA 1-50)

This 兔 多克隆 antibody specifically detects Apoptosis Inhibitor 5 in WB, IP 和 IHC (fp). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7453657
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Apoptosis Inhibitor 5 抗体 (AA 1-50) (ABIN7453657)

抗原

See all Apoptosis Inhibitor 5 (API5) 抗体
Apoptosis Inhibitor 5 (API5)

适用

  • 42
  • 29
  • 9
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 56
  • 2

克隆类型

  • 56
  • 2
多克隆

标记

  • 24
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Apoptosis Inhibitor 5 antibody is un-conjugated

应用范围

  • 42
  • 21
  • 14
  • 14
  • 9
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 16
    • 11
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50

    原理

    Rabbit anti-API5 Antibody, Affinity Purified

    预测反应

    X. laevis,Chicken,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Apoptosis Inhibitor 5 (API5)

    别名

    API5

    背景

    Background: API5 (apoptosis inhibitor 5) is an antiapoptotic factor that may have a role in protein assembly. API5 negatively regulates ACIN1. By binding to ACIN1, API5 suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. API5 is also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

    基因ID

    8539

    NCBI登录号

    XP_508375

    UniProt

    Q9BZZ5

    途径

    Growth Factor Binding
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