DLGAP5 抗体 (AA 200-250)
Quick Overview for DLGAP5 抗体 (AA 200-250) (ABIN7453633)
抗原
See all DLGAP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-250
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原理
- Rabbit anti-HURP/DLG7 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 200 and 250
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- DLGAP5 (Discs, Large (Drosophila) Homolog-Associated Protein 5 (DLGAP5))
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别名
- HURP/DLG7
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背景
- Background: HURP/DLG7 (Hepatoma Up-Regulated Protein/Disks Large Homolog 7) is a member of the MAGUK (membrane-associated guanylate kinase) family of scaffolding proteins. There are seven DLG homologs in mammals that play important roles in regulating proliferation, epithelial cell polarity, cell adhesion, and synapse formation. HURP/DLG7 has been identified as a microtubule-associated protein (MAP) that colocalizes with the mitotic spindle and functions as a mitotic regulator. HURP/DLG7 is required for microtubule attachment and efficient capture of kinetochores, as well as timely chromosome congression. HURP/DLG7 is up-regulated in human cancer cells and may contribute to tumorigenesis.
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基因ID
- 9787
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NCBI登录号
- NP_055565
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UniProt
- Q15398
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途径
- M Phase
抗原
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