FHL2 抗体 (C-Term)
Quick Overview for FHL2 抗体 (C-Term) (ABIN7453598)
抗原
See all FHL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-FHL2 Antibody, Affinity Purified
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预测反应
- Rat,Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 225 and C-term
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亚型
- IgG
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应用备注
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IHC: 1:1,000 to 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FHL2 (Four and A Half LIM Domains 2 (FHL2))
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别名
- FHL2
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背景
- Background: FHL2 is a member of the four-and-a-half-LIM-domain protein family which consists of FHL1, FHL2, FHL3, FHL4, and ACT. The LIM domain is a cysteine-rich motif that mediates protein-protein interactions. FHL2 has been shown to function as a transcriptional cofactor and through its LIM domains, interact with a variety of factors which include the androgen receptor, CREB, AP-1, Runx3, SRF, FOXO1, BRCA1 and the HPV-16 E7 oncoprotein. FHL2 has been demonstrated to play an important role in heart and bone development and may influence cancer cell growth.
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基因ID
- 2274
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NCBI登录号
- NP_963849
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UniProt
- Q14192
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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