Cyclin C 抗体 (AA 233-283)
Quick Overview for Cyclin C 抗体 (AA 233-283) (ABIN7453580)
抗原
See all Cyclin C (CCNC) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 233-283
-
原理
- Rabbit anti-Cyclin C Antibody, Affinity Purified
-
预测反应
- Mouse,Rat,Chicken,Bovine
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 233 and 283
-
亚型
- IgG
-
-
-
-
应用备注
-
IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- Cyclin C (CCNC)
-
别名
- Cyclin C
-
背景
- Background: Cyclin C is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression. Cyclins exhibit periodicity in their expression and activity which is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin C associates with cyclin-dependent kinase 8 (CDK8). It is also a component of the Mediator complex, a coactivator complex that provides a scaffold to link gene-specific transcription factors to RNA polymerase II and the general transcription machinery.
-
基因ID
- 892
-
NCBI登录号
- NP_005181
-
UniProt
- P24863
-
途径
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
抗原
-