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Cyclin C 抗体 (AA 233-283)

The 兔 多克隆 anti-Cyclin C antibody is suitable to detect Cyclin C in samples from 人. It has been validated for WB, IP 和 IHC (fp).
产品编号 ABIN7453580
发货至: 中国
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Quick Overview for Cyclin C 抗体 (AA 233-283) (ABIN7453580)

抗原

See all Cyclin C (CCNC) 抗体
Cyclin C (CCNC)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cyclin C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 233-283

    原理

    Rabbit anti-Cyclin C Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Chicken,Bovine

    纯化方法

    Affinity Purified

    免疫原

    between AA 233 and 283

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Cyclin C (CCNC)

    别名

    Cyclin C

    背景

    Background: Cyclin C is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression. Cyclins exhibit periodicity in their expression and activity which is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin C associates with cyclin-dependent kinase 8 (CDK8). It is also a component of the Mediator complex, a coactivator complex that provides a scaffold to link gene-specific transcription factors to RNA polymerase II and the general transcription machinery.

    基因ID

    892

    NCBI登录号

    NP_005181

    UniProt

    P24863

    途径

    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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