USP1 抗体 (AA 450-500)
Quick Overview for USP1 抗体 (AA 450-500) (ABIN7453545)
抗原
See all USP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-500
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原理
- Rabbit anti-USP1 Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 450 and 500
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 1 (USP1) (AA 453-592) antibody
USP1 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) (AA 701-785) antibodyUSP1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) (C-Term) antibodyUSP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) antibodyUSP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) (AA 1-785) antibodyUSP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) (AA 701-750) antibodyUSP1 适用: 人, 小鼠, 犬, 马, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) (AA 486-785) antibodyUSP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) (AA 1-198) antibodyUSP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) (AA 607-637), (C-Term) antibodyUSP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4199 unconjugated
anti-Ubiquitin Specific Peptidase 1 (USP1) (C-Term) antibodyUSP1 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7453545 has not performed satisfactorily when used for WB of USP1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of USP1.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- USP1 (Ubiquitin Specific Peptidase 1 (USP1))
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别名
- USP1
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背景
- Background: Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 1 (USP1) has been found to play a role in the Fanconi anemia DNA repair pathway. USP1 specifically removes monoubiquitination from the Fanconi anemia D2 (FANCD2) protein and from the proliferating cell nuclear antigen (PCNA). Deubiquitination of FANCD2 and PCNA is critical to their role in the DNA damage response and DNA crosslink repair.
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基因ID
- 7398
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NCBI登录号
- NP_003359
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UniProt
- O94782
抗原
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