NPAT 抗体 (AA 700-750)
This anti-NPAT antibody is a 兔 多克隆 antibody detecting NPAT in WB, IP 和 IHC (fp). Suitable for 人.
Quick Overview for NPAT 抗体 (AA 700-750) (ABIN7453506)
抗原
See all NPAT 抗体
NPAT
(Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))
适用
人
宿主
兔
克隆类型
多克隆
标记
This NPAT antibody is un-conjugated
应用范围
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
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抗原表位
- AA 700-750
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原理
- Rabbit anti-NPAT Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 700 and 750
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亚型
- IgG
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anti-Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT) antibody
NPAT 适用: 人 DB 宿主: 小鼠 Monoclonal 2648C6a unconjugated
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-NPAT antibody ABIN7453485.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))
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别名
- NPAT
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背景
- Background: NPAT (nuclear protein of the ataxia telangiectasia mutated locus) is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. NPAT also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14207].
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基因ID
- 4863
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NCBI登录号
- NP_002510
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UniProt
- Q14207
抗原
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