GTF2IRD/TFII-IRD1 (AA 650-700) 抗体
This 兔 多克隆 antibody specifically detects GTF2IRD/TFII-IRD1 in WB, IHC (fp) 和 IP. It exhibits reactivity toward 人.
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产品编号 ABIN7453501
发货至:
中国
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Quick Overview for GTF2IRD/TFII-IRD1 (AA 650-700) 抗体 (ABIN7453501)
抗原
GTF2IRD/TFII-IRD1
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)
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抗原表位
- AA 650-700
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原理
- Rabbit anti-GTF2IRD/TFII-IRD1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 650 and 700
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亚型
- IgG
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anti-GTF2IRD/TFII-IRD1 (AA 650-700) antibody
适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-GTF2IRD/TFII-IRD1 antibody ABIN7449370.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- GTF2IRD/TFII-IRD1
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背景
- Background: GTF2IRD1/TFII-IRD1 possesses five helix-loop-helix GTF2I-like repeats and has been shown to bind the GUCE (GTF2IRD1 upstream response element) regulatory motif found in HOXC8, GOOSECOID, and TROPONININ (SLOW) genes. GTF2IRD1/TFII-IRD1 may be involved in skeletal muscle differentiation and myogenesis. Haploinsufficiency of GTF2IRD1/TFII-IRD1 results in Williams-Beuren syndrome (WBS), a rare developmental disorder characterized by musculo-skeletal and cardiac abnormalities.
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基因ID
- 9569
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NCBI登录号
- NP_057412
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UniProt
- Q9UHL9
抗原
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