CAND1 抗体 (AA 1180-1230)
Quick Overview for CAND1 抗体 (AA 1180-1230) (ABIN7453479)
抗原
See all CAND1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 1180-1230
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                                            原理
- Rabbit anti-CAND1 Antibody, Affinity Purified
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                                            预测反应
- Rat,Bovine,Orangutan
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- between AA 1180 and 1230
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                                            亚型
- IgG
 
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                                            应用备注
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                        IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. IP: 2 - 5 μg/mg lysate WB: 1:2,000 - 1:10,000 
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                                            限制
- 仅限研究用
 
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                                            浓度
- 1000 μg/mL
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                                            缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C
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                                            有效期
- 12 months
 
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    - CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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                                            别名
- CAND1
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                                            背景
- Background: Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) Q86VP6].
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                                            基因ID
- 55832
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                                            NCBI登录号
- NP_060918
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                                            UniProt
- Q86VP6
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                                            途径
- Regulation of Actin Filament Polymerization
 抗原
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