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THO Complex 4 抗体 (AA 25-75)

This 兔 多克隆 antibody specifically detects THO Complex 4 in WB, IP 和 IHC (fp). It exhibits reactivity toward 人.
产品编号 ABIN7453477
发货至: 中国
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Quick Overview for THO Complex 4 抗体 (AA 25-75) (ABIN7453477)

抗原

See all THO Complex 4 (THOC4) 抗体
THO Complex 4 (THOC4)

适用

  • 54
  • 30
  • 20
  • 3
  • 3
  • 2
  • 1
  • 1

宿主

  • 51
  • 3

克隆类型

  • 38
  • 16
多克隆

标记

  • 29
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This THO Complex 4 antibody is un-conjugated

应用范围

  • 41
  • 21
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  • 8
  • 2
  • 2
  • 2
  • 1
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-75

    原理

    Rabbit anti-Aly Antibody, Affinity Purified

    预测反应

    Bovine

    纯化方法

    Affinity Purified

    免疫原

    between AA 25 and 75

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    THO Complex 4 (THOC4)

    别名

    Aly

    背景

    Background: Aly (ally of AML-1 and LEF-1) is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. Aly also functions as a chaperone and promotes the dimerization of transcription factors containing basic leucine zipper (bZIP) domains and thereby promotes transcriptional activation. Additionally, Aly plays a role in mRNA processing and export and may function as scaffold that mediates interactions between proteins and/or RNA. Aly is also part of the exon junction complex that remains associated with spliced mRNA and plays an important role in mRNA export and nonsense-mediated RNA decay. Aly directs mRNA derived from Herpes simplex virus intron-less genes to the NXF1-mediated export pathway [taken from the Universal Protein Resource (UniProt) Q886V81].

    基因ID

    10189

    UniProt

    Q86V81
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