hPrp3p (AA 100-150) 抗体
The 兔 多克隆 anti-hPrp3p antibody (ABIN7453461) specifically detects hPrp3p in IP, IHC (fp) 和 WB.
The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7453461
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for hPrp3p (AA 100-150) 抗体 (ABIN7453461)
抗原
hPrp3p
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Western Blotting (WB)
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抗原表位
- AA 100-150
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原理
- Rabbit anti-hPrp3p Antibody, Affinity Purified
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预测反应
- Chicken,Bovine,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 100 and 150
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亚型
- IgG
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anti-hPrp3p (AA 100-150) antibody
适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7453461 has not performed satisfactorily when used for WB of hPrp3p in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of hPrp3p.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- hPrp3p
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背景
- Background: hPrp3p (human pre-mRNA splicing factor 3) was identified as a factor that associated with U4/U6 snRNPs which are components of the splicesome. hPrp3p is homologous to S. cerevisiae splicing factor Prp3p. Mutations in the PRPF3 gene are associated with retinitis pigmentosa-18. It has been determined that mutations in hPrp3p may alter the recognition motif for phosphorylation by casein kinase II (CKII) and that loss of phosphorylation may result in aberrant interactions within the U4/U6 snRNP complex.
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基因ID
- 9129
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NCBI登录号
- NP_004689
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UniProt
- O43395
抗原
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