TBL1XR1 抗体 (AA 100-150)
Quick Overview for TBL1XR1 抗体 (AA 100-150) (ABIN7453451)
抗原
See all TBL1XR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-150
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原理
- Rabbit anti-TBLR1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 100 and 150
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亚型
- IgG
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))
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别名
- TBLR1
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背景
- Background: TBLR1 is a six WD-40 repeat protein with high sequence homology to TBL1 (transducin beta-like protein 1) and is part of the SMRT (silencing mediator of retinoid and thyroid hormone receptors) and N-CoR (nuclear receptor corepressor) complexes that interact with nuclear receptors and repress transcription. Biochemical characterization of SMRT and N-CoR complexes demonstrate that SMRT and N-CoR are present in complexes that include HDAC3 (histone deacetylase 3), TBL1, and TBLR1. Association with HDAC3 indicates that these complexes may repress transcription through histone deacetylation and chromatin remodeling.
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基因ID
- 79718
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NCBI登录号
- NP_078941
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UniProt
- Q9BZK7
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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