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BRD4 抗体 (AA 1312-1362)

This anti-BRD4 antibody is a 兔 多克隆 antibody detecting BRD4 in WB, IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7453424
发货至: 中国

Quick Overview for BRD4 抗体 (AA 1312-1362) (ABIN7453424)

抗原

See all BRD4 抗体
BRD4 (Bromodomain Containing 4 (BRD4))

适用

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人, 小鼠

宿主

  • 70
  • 2
  • 1

克隆类型

  • 59
  • 13
  • 1
多克隆

标记

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This BRD4 antibody is un-conjugated

应用范围

  • 45
  • 37
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  • 1
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 13
    • 10
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 1312-1362

    原理

    Rabbit anti-BRD4 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1312 and 1362

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    BRD4 (Bromodomain Containing 4 (BRD4))

    别名

    BRD4

    背景

    Background: Bromodomain-containing protein 4 (BRD4) contains 2 bromo-domains. Bromo-domains are found in chromatin-associating proteins and can interact specifically with acetylated lysine. BRD4 is described as a chromatin adaptor and has been shown to bind acetylated chromatin. It was originally identified as MCAP (mitotic chromosome associated protein) due to its association with mitotic chromosomes. BRD4 also associates with several transcription complexes such as the Mediator complexes and P-TEFb complexes and is considered to function as a transcriptional co-factor.

    基因ID

    23476

    NCBI登录号

    NP_490597

    UniProt

    O60885

    途径

    Chromatin Binding, SARS-CoV-2 Protein Interactome
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