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Prohibitin 2 抗体 (AA 1-50)

This anti-Prohibitin 2 antibody is a 兔 多克隆 antibody detecting Prohibitin 2 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453408
发货至: 中国

Quick Overview for Prohibitin 2 抗体 (AA 1-50) (ABIN7453408)

抗原

See all Prohibitin 2 (PHB2) 抗体
Prohibitin 2 (PHB2)

适用

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  • 1
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宿主

  • 78
  • 3
  • 2

克隆类型

  • 77
  • 6
多克隆

标记

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This Prohibitin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 16
    • 11
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    AA 1-50

    原理

    Rabbit anti-REA Antibody, Affinity Purified

    预测反应

    Mouse,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 1 - 4 μg/mg lysate

    WB: Not recommended. Use rabbit anti-REA Antibodies Cat. No. ABIN7450649 or Cat No. ABIN7449571.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Prohibitin 2 (PHB2)

    别名

    REA

    背景

    Background: REA (repressor of estrogen receptor activity), also known as prohibitin 2, has been shown to exhibit a variety of functions that includes mitochondrial chaperone activity, cell cycle regulation, and transcriptional regulation. REA localizes to the mitochondria and associates with mitochondrial complex I where it may play a role in mitochondrial metabolism. REA interacts with pRb to inhibit E2F-mediated transcription as well as the estrogen receptor to repress estrogen-dependent transcription via recruitment of histone deacetylases.

    基因ID

    11331

    NCBI登录号

    NP_009204

    UniProt

    Q99623

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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