BCR 抗体 (AA 1221-1271)
Quick Overview for BCR 抗体 (AA 1221-1271) (ABIN7453394)
抗原
See all BCR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1221-1271
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原理
- Rabbit anti-BCR Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 1221 and 1271
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亚型
- IgG
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应用备注
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ICC-IF: 1:500 - 1:2,000
IP: 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BCR (Breakpoint Cluster Region (BCR))
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别名
- BCR
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背景
- Background: BCR (breakpoint cluster region) was identified as part of a fusion protein that results from a reciprocal translocation with the ABL gene between chromosomes 22 and 9. The BCR-ABL fusion is the cause of chronic myeloid leukemia (CML). The BCR protein contains a C2 domain, a DBL-homology domain, a PH domain, and a Rho-GAP domain and functions as a GTPase-activating protein for RAC1 and CDC42.
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基因ID
- 613
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NCBI登录号
- NP_004318
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UniProt
- P11274
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途径
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
抗原
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